📜The lab’s 1st publication is posted

We are stoked to share about the lab’s 1st publication on what gets the heart cells contracting and relaxing.

https://www.biorxiv.org/content/10.1101/2025.10.03.680406v1

👉🏼In this work, we show that two proteins play see-saw to oversee a cell signaling pathway that’s important in heart function control. These results have implications for treating patients with a form of heart failure.

👉🏼👉🏼Phosphodiesterase type 1 regulates the pool of cAMP associated with adenosine 2A but not 2B receptor stimulation. This is important in heart contractility in both health and disease. Not all GPCRs are the same – even when they share so much by their names.